2-chloro-5-hydroxypyridine-3-carboxylic acid

2-chloro-5-hydroxypyridine-3-carboxylic acid - Names and Identifiers

Name	2-chloro-5-hydroxypyridine-3-carboxylic acid
Synonyms	42959-40-0 2-Chloro-5-hydroxynicotinic acid 2-chloro-5-hydroxypyridine-3-carboxylic acid 2-Chloro-5-hydroxy-3-pyridinecarboxylic acid 3-Pyridinecarboxylicacid, 2-chloro-5-hydroxy- 3-pyridinecarboxylic acid, 2-chloro-5-hydroxy-
CAS	42959-40-0
InChI	InChI=1/C6H4ClNO3/c7-5-4(6(10)11)1-3(9)2-8-5/h1-2,9H,(H,10,11)

2-chloro-5-hydroxypyridine-3-carboxylic acid - Physico-chemical Properties

Molecular Formula	C6H4ClNO3
Molar Mass	173.55
Density	1.643±0.06 g/cm3(Predicted)
Melting Point	236-237 °C (decomp)
Boling Point	530.1±50.0 °C(Predicted)
Flash Point	274.372°C
Vapor Presure	0mmHg at 25°C
pKa	0.30±0.25(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.64

2-chloro-5-hydroxypyridine-3-carboxylic acid - Introduction

Acid is an organic compound with the chemical formula C6H4ClNO3. It is a white crystalline solid, soluble in water at room temperature.

Its main use is as a pharmaceutical intermediate, especially in the synthesis of antibacterial drugs, antiviral drugs and pesticides play a key role. It can be used for the synthesis of pyrrolidine tetrazole antibiotics, piperazine antibiotics, furan antibiotics and other drugs.

The preparation method of hydrochloric acid can generally be achieved in a variety of ways, such as through the hydrolysis reaction of 3-chloro nicotinic acid. The specific preparation method can refer to the relevant organic synthesis literature.

The compound is generally safe under proper handling and storage conditions, but the following safety information should be noted:
-Avoid direct contact with the eyes and skin, such as accidental contact should immediately rinse with plenty of water.
-Avoid inhaling its dust or gas, and operate in a well-ventilated place.
-Before use, read and understand the relevant safety technical instructions, and wear appropriate protective equipment, such as gloves, glasses and respirators.
-Observe local safety regulations and regulations during use, storage and handling.

Last Update：2024-04-09 18:58:34